Welcome to AlzSWAN

Where you explore scientific knowledge about Alzheimer disease and share your own ideas, comments and questions in a semantically structured system.

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» FEATURED CONTRIBUTIONS

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» HOT TOPICS (browse all hypotheses)

Changes in presenilin function lead to dementia and neurodegeneration in Alzheimer Disease

Misfolded proteins accumulated into protein aggregates characterizes the pathologic lesions of AD

The molecular mechanisms of neuronal cell death are involved in the dysfunction and death of neurons in AD

Synaptic loss appears to be the most powerful and ubiquitous proximate factor leading to the dementia of AD

Failure of axonal transport might be the underlying basis for neurodegeneration in AD

» MECHANISMS

» HOW TO CONTRIBUTE

BUILD A HYPOTHESIS
CRITIQUE A HYPOTHESIS
NOMINATE A KEY PAPER
HELP FIND CONNECTIONS
PROPOSE NEW FEATURES
ADD SUPPORTING EVIDENCE

» KNOWLEDGE BASE

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Content contained on AlzSWAN made available under Creative Commons license - See AlzSWAN Terms of Use