


{"items":[{"lsescontent":"[<a href=\"http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090\" style=\"display: inline; white-space: nowrap;\" target=\"_blank\"><img src=\"/swan/images/browser/externalLink.gif\" border=\"0\">Mus musculus<\/a>]: <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:gene:478560c4-6606-4298-95d5-1b124718fbcf\" title=\"Gene: Nrg1 neuregulin 1 [Mus musculus]\">Nrg1<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:gene:efa39cbb-0770-4f11-a77a-e88d75ac475b\" title=\"Gene: Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) [Mus musculus]\">Erbb3<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:gene:097c20ab-82ac-4ca0-9068-69934f2baa5b\" title=\"Gene: Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) [Mus musculus]\">Erbb4<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:protein:7e50466d-7685-42dc-9b5f-75fa7e8c5587\" title=\"Protein: Receptor tyrosine-protein kinase erbB-3 [Mus musculus]\">Receptor tyrosine-protein kinase erbB-3<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:protein:2bbb6a9f-0445-48b9-b8a6-56aef64e93e4\" title=\"Protein: Receptor tyrosine-protein kinase erbB-4 [Mus musculus]\">Receptor tyrosine-protein kinase erbB-4<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:gene:d7539109-ff19-4495-854b-1bb348d0a361\" title=\"Gene: Olig2 oligodendrocyte transcription factor 2 [Mus musculus]\">Olig2<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:protein:ecb92bdb-3dec-4dd7-8fb4-903a436810c3\" title=\"Protein: Myelin basic protein [Mus musculus]\">Myelin basic protein<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:protein:2f95225a-03e1-4e55-b1e9-1b563d5946be\" title=\"Protein: Oligodendrocyte transcription factor 2 [Mus musculus]\">Oligodendrocyte transcription factor 2<\/a>, <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:gene:ad089014-b72e-4592-a6d4-4b421dc6339a\" title=\"Gene: Mbp myelin basic protein [Mus musculus]\">Mbp<\/a>; ","refutedbylink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b&selectContainedDiscourseElementCriteria=hasRefutesOrRefutedByDiscourseElements&referrerLinkLabel=structuredcommentslist","lsid":"urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b","containedwithevidence":4,"relatedToOthers":"true","title":"Barres comment on Bartzokis hypothesis \"The human brain\u2019s myelin sheaths underlie a unique vulnerability to Alzheimer Disease (AD).\"","type":"Comment","containedevidencecountlink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b&selectContainedDiscourseElementCriteria=hasTotalEvidence&referrerLinkLabel=structuredcommentslist","contained":4,"refutedby":1,"status":"Extended Annotation","alternativetolink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b&selectContainedDiscourseElementCriteria=alternativeToOtherDiscourseElements&referrerLinkLabel=structuredcommentslist","id":"urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b","containedevidencecount":4,"alternativeto":2,"lsidUrl":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b&referrerLinkLabel=structuredcommentslist","label":"Barres B; Barres comment on Bartzokis hypothesis \"...","icon":"../icons/ontological/discourse-element/comment.png","containedwithoutevidence":0,"firstAuthor":"Barres Ben A","lses":"true","containedwithevidencelink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:b146c9be-ea9d-46d1-b243-4207443d552b&selectContainedDiscourseElementCriteria=hasEvidence&referrerLinkLabel=structuredcommentslist"},{"lsidUrl":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:c55b6358-ec31-4568-b165-dc41bc060e44&referrerLinkLabel=structuredcommentslist","lsid":"urn:lsid:swan.org:comment:c55b6358-ec31-4568-b165-dc41bc060e44","type":"Comment","title":"Disruption in electrical activity and synaptic transmission precedes beta amyloid formation and cognitive deficits by months.  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white-space: nowrap;\" target=\"_blank\"><img src=\"/swan/images/browser/externalLink.gif\" border=\"0\">Homo sapiens<\/a>]: <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:protein:3d200519-3f9e-42ea-b02b-819ce6ba24c4\" title=\"Protein: Major prion protein [Homo sapiens]\">Major prion protein<\/a>; [<a href=\"http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090\" style=\"display: inline; white-space: nowrap;\" target=\"_blank\"><img src=\"/swan/images/browser/externalLink.gif\" border=\"0\">Mus musculus<\/a>]: <a href=\"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:protein:3f1c2123-3519-488e-b7fc-427024d8e244\" title=\"Protein: Major prion protein [Mus musculus]\">Major prion protein<\/a>; ","containedwithoutevidencelink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e&selectContainedDiscourseElementCriteria=hasNoEvidence&referrerLinkLabel=structuredcommentslist","containedwithevidence":1,"lsid":"urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e","relatedToOthers":"true","title":"Prado comment on Laurén et al hypothesis \"Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers.\"","type":"Comment","containedevidencecountlink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e&selectContainedDiscourseElementCriteria=hasTotalEvidence&referrerLinkLabel=structuredcommentslist","contained":2,"status":"Extended Annotation","referenceDate":"2009-03-24","id":"urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e","supportedbylink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e&selectContainedDiscourseElementCriteria=hasSupportOrSupportedByDiscourseElements&referrerLinkLabel=structuredcommentslist","containedevidencecount":1,"lsidUrl":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e&referrerLinkLabel=structuredcommentslist","label":"Prado M; Prado comment on Laurén et al hypothesis...","supportedby":1,"icon":"../icons/ontological/discourse-element/comment.png","containedwithoutevidence":1,"firstAuthor":"Prado Marco","referenceYear":"2009","lses":"true","containedwithevidencelink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:01feade7-2f67-4609-b1b1-1064658bfd3e&selectContainedDiscourseElementCriteria=hasEvidence&referrerLinkLabel=structuredcommentslist"},{"containedwithoutevidencelink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:15ae5868-04c0-4fc0-8e94-ef1d8deae4d0&selectContainedDiscourseElementCriteria=hasNoEvidence&referrerLinkLabel=structuredcommentslist","containedwithevidence":0,"lsid":"urn:lsid:swan.org:comment:15ae5868-04c0-4fc0-8e94-ef1d8deae4d0","relatedToOthers":"true","title":"Wolozin comment on Walsh hypothesis \u201cNaturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.\u201d","type":"Comment","contained":2,"status":"Extended Annotation","referenceDate":"2002-06-05","id":"urn:lsid:swan.org:comment:15ae5868-04c0-4fc0-8e94-ef1d8deae4d0","supportedbylink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:15ae5868-04c0-4fc0-8e94-ef1d8deae4d0&selectContainedDiscourseElementCriteria=hasSupportOrSupportedByDiscourseElements&referrerLinkLabel=structuredcommentslist","discussedbylink":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:15ae5868-04c0-4fc0-8e94-ef1d8deae4d0&selectContainedDiscourseElementCriteria=discussedByOtherDiscourseElements&referrerLinkLabel=structuredcommentslist","containedevidencecount":0,"lsidUrl":"/swan/browser/showEntity.action?objectId=urn:lsid:swan.org:comment:15ae5868-04c0-4fc0-8e94-ef1d8deae4d0&referrerLinkLabel=structuredcommentslist","label":"Wolozin B; Wolozin comment on Walsh hypothesis \u201cNat...","supportedby":1,"icon":"../icons/ontological/discourse-element/comment.png","discussedby":1,"containedwithoutevidence":2,"firstAuthor":"Wolozin B","referenceYear":"2002"}]}
